pentobarbital will decrease the extent or result of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will lower the extent or result of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. If coadministration that has a CYP3A4 inducer is critical, conside